Zithromax vs. Augmentin vs. Doxycycline: Antibiotics Compared

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Difference between Zithromax, Augmentin and Doxycycline

Antibiotics of all kinds can be obtained from pharmacies nowadays, and it can be confusing to figure out which one you need. Zithromax, Augmentin, and Doxycycline are only three such antibiotics, and they are generally used in the treatment of a wide variety of conditions. Let's see how the three differ.



Zithromax is an antibiotic of the macrolide variety. It is related to erythromycin, and works by controlling the bacteria in the body.

Augmentin is a form of penicillin antibiotic. It is comprised of amoxicillin and clavulanate potassium. Amoxicillin is a type of penicillin that fights bacteria in the body, while clavulanate potassium (which is a type of clavulanic acid) is used to counteract bacterial resistance to amoxicillin.

Doxycycline is a type of antibiotic in the tetracycline category. It works by slowing down the rate of growth of bacteria.

What It’s Used For

Zithromax can be used for many types of bacterial infections, among them respiratory, skin, and ear infections. It is also used in the treatment of some types of bacteria related sexually transmitted diseases. Zithromax is also often used in the treatment of middle ear infections, pneumonia, tonsillitis, and strep throat in children.

Augmentin is commonly used in the treatment of various types of bacterial infections, among them sinusitis, pneumonia, ear infections, bronchitis, and skin infections. It is also used in the treatment of urinary tract infection.

Doxycycline is often prescribed for the treatment of certain types of bacterial infections, among them urinary tract infection, gonorrhea, chlamydia, periodontitis, and even acne. In some cases, this medication may also be used in the treatment of skin blemishes, bumps, and acne-like outbreaks that result from rosacea, although it will not have an effect on the redness caused by the condition.

Risks and Precautions

Zithromax should not be used by people who have had allergic reactions to azithromycin or erythromycin, or clarithromycin, telithromycin, or troleandomycin. In addition, there are several other drugs that may cause an adverse reaction when used with Zithromax.

The use of Augmentin is not recommended for patients with allergies to amoxicillin or clavulanate potassium, or this who have liver conditions caused by such medications. Patients who have allergies to other types of penicillin antibiotics should also avoid using Augmentin. It would also be a good idea to tell your doctor about the existence of liver or kidney disease, or mononucleosis.

Doxycycline should not be used by women who are pregnant or those who are trying to become pregnant. In addition, you should also be aware that Doxycycline may cause a decrease in the effectiveness of certain birth control pills.

Similarities and Differences


  • An antibiotic of the macrolide variety
  • Works by controlling the bacteria in the body


  • A form of penicillin antibiotic
  • Comprised of amoxicillin and clavulanate potassium


  • A type of antibiotic in the tetracycline category
  • May cause a decrease in the effectiveness of certain birth control pills

Which antibiotic med is prescribed most often?
  • Zithromax
  • Augmentin
  • Doxycycline

Discuss It: comments 4

  • Guest
  • Rick Ladd wrote on June 2011

I have had a recurrent rash blistering effect on the head of my **** off and on for years. I have just realised that it is an allergic reaction to doxycycline. The last time I took the antibiotic I developed a rash when I had an upper respiratory infection. I wasn't sure what had caused it. But I took one doxycycline the other day because I could feel myself getting an upper respiratory chest infection again, the next day the same pattern was starting on the head of my ****. So I never took any more again, applied 1% hydrocortisone cream and it started to go away very quickly. I have noticed that others have reported this same side effect on doxycycline.

@ Rick - maybe it's because you're rubbing your **** too hard with a belt sander. In my experience, application of a 3400 rpm sanding block can cause **** blisters, **** rashes and other **** ailments. I'd suggest you begin applying a mixture of zinc oxide and caumine lotion to the head of your **** every six to seven hours, then wrapping it in a compress of warm meat. It should begin to heal in 3-4 days with total healing in 2 weeks. Once fully healed, you should reduce the RPM setting on your sander and consider a finer grit of sanding paper when sanding the head of your ****. It worked for me!

-Dr. MOG.

  • Guest
  • Lily Bourbour wrote on September 2014

I have two children 47 and forty.

After the age of 5 and finish with Vaccination

I never took them to doctor.

I just when to pharmacy.

I lived in Europe.

  • Guest
  • Lily Bourbour wrote on September 2014

pharmaceutical companies.

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